Arizona elevates Josiah Deguara from the practice squad to serve as a fourth tight end in Week 2 against Carolina, a rare depth move for the Cardinals. With Tip Reiman sidelined and Joey Blount on IR, Deguara’s special-teams prowess and blocking know-how bolster depth while Elijah Higgins and Travis Vokolek absorb more inline duties. Expect the offense to lean on blocking and short-yardage plays, not heavy TE targets in standard leagues.

Carolina did not make roster moves, so Arizona can deploy its four-TE look with familiar pieces. For fantasy managers, monitor how much Deguara contributes on offense beyond special teams, and whether Higgins or Vokolek carve into red-zone opportunities or stay primarily blockers in Week 2.

New Orleans faces a tough test as Spencer Rattler and a battered offense host San Francisco. With Taysom Hill, Foster Moreau, Trevor Penning, and potentially Taliese Fuaga sidelined, the Saints must push a more efficient passing game and smarter play design to avoid an 0-2 start.

For fantasy managers, focus on Rashid Shaheed, Chris Olave, and Alvin Kamara as the trio most likely to produce targets and yards if the Saints unlock play-action and get the ball into space. San Francisco’s defense remains elite up front and in coverage, so protection and precision from Kellen Moore and Rattler will be pivotal for any redemption day in week 2.

Panthers are 0-1 after a flat opener with Jacksonville; Cardinals are 1-0 after a win over New Orleans. The Week 2 clash in Glendale tests Carolina's young core and Arizona's fresh momentum, with Arizona favored by 6.5 and eager to push toward a 2-0 start.

Bryce Young must rebound and Carolina's defense must clamp down; Chuba Hubbard could push for more touches if Carolina trails, while Budda Baker's presence on defense and the Cardinals' late-game execution will be key fantasy pivots in this matchup.